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Figure 4. Spiral wave front and the tip trajectory. A, Tip trajectory computed from four revolutions of the spiral wave when potassium conductance (gK) was 1.13. The leading edge of the spiral wavefront is black, and the trajectory followed by the tip is gray. The white background represents rested or refractory cells. A small, four-petaled flower was inscribed within the region illustrated in Fig 3A. When the gK was reduced to 0.75, the action potential duration increased, which increased the instability of the core, resulting in an increase in the number of petals and the size of the flower. B, Tip trajectory computed from six and one half revolutions of the spiral wave. As the tip of the spiral moves from one extreme of the flower to another, the computed ECG is influenced and both the morphology of the electrogram and its amplitude are modulated.




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